Cancer

During tumor progression, cancer cells adapt to changes in the microenvironment (lack of nutrients and /or oxygen) through the activation of stress pathways and autophagy...

The Cell Cycle group studies the molecular mechanisms that regulate the division of eukaryotic cells, in particular: (A) the mechanisms dependent on SUMO and SMC complexes that ensure genome stability during the cycle and in response to DNA damage...

The team's goal is to study the molecular mechanisms that take place during embryonic development to form a complete and functional organism and how these mechanisms are affected in pathological situations such as cancer...

Our research group embodies a multidisciplinary approach, encompassing diverse research lines that delve into both basic and translational research...

The main interest of our laboratory is the study of the molecular events underlying the oncogenic process in colorectal, gastric, head-and-neck and endometrial cancer...

The group studies the molecular alterations of endometrial and skin cancers, in correlation with clinical and pathological characteristics, using descriptive molecular pathology tools (immunohistochemistry, in situ hybridization, sequencing, epigenetics, gene gain and loss), as well as in vitro functional analysis in cell cultures (2D and 3D), and experimental animals...

Our research group is translational, multidisciplinary and young. It is composed of medical doctors specialized in Medical Oncology, Internal Medicine, Radiotherapy Oncology and Clinical Analysis; and basic researchers trained in Biosciences (Biology, Biochemistry, Biomedicine and Biotechnology) with a high degree of cohesion...