Fisiopatologia metabòlica
Responsable de grup
Publicacions (413)
Pamplona, Reinald; Barja, Gustavo
Highly resistant macromolecular components and low rate of generation of endogenous damage: two key traits of longevity.
AGEING RESEARCH REVIEWS 6 189-210. .
Cantero, Anne-Valerie; Portero-Otin, Manuel; Ayala, Victoria; Auge, Nathalie; Sanson, Marie; Elbaz, Meyer; Thiers, Jean-Claude; Pamplona, Reinald; Salvayre, Robert; Negre-Salvayre, Anne
Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis.
FASEB JOURNAL 21 3096-3106. .
Hulbert, A. J.; Pamplona, Reinald; Buffenstein, Rochelle; Buttemer, W. A.
Life and death: metabolic rate, membrane composition, and life span of animals.
Physiological Reviews 87 1175-1213. .
Espada, Lilia; Udapudi, Basavaraj; Podlesniy, Petar; Fabregat, Isabel; Espinet, Carme; Tauler, Albert
Apoptotic action of E2F1 requires glycogen synthase kinase 3-beta activity in PC12 cells
JOURNAL OF NEUROCHEMISTRY 102 2020-2028. .
Brunet, Nuria; Tarabal, Olga; Portero-Otin, Manel; Oppenheim, Ronald W.; Esquerda, Josep E.; Caldero, Jordi
Survival and death of mature avian motoneurons in organotypic slice culture: trophic requirements for survival and different types of degeneration.
JOURNAL OF COMPARATIVE NEUROLOGY 501 669-690. .
Ayala, Victoria; Naudi, Alba; Sanz, Alberto; Caro, Pilar; Portero-Otin, Manuel; Barja, Gustavo; Pamplona, Reinald
Dietary protein restriction decreases oxidative protein damage, peroxidizability index, and mitochondrial complex I content in rat liver.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 62 352-360. .
Caro, Pilar; Gomez, Jose; Sanz, Alberto; Portero-Otin, Manel; Pamplona, Reinald; Barja, Gustavo
Effect of graded corticosterone treatment on aging-related markers of oxidative stress in rat liver mitochondria.
Biogerontology 8 1-11. .
Ribera, Joan; Ayala, Victoria; Casas, Celia
Involvement of c-Jun-JNK pathways in the regulation of programmed cell death of developing chick embryo spinal cord motoneurons.
DEVELOPMENTAL NEUROSCIENCE 29 438-451. .
Muntane, G.; Dalfo, E.; Martinez, A.; Rey, M. J.; Avila, J.; Perez, M.; Portero, M.; Pamplona, R.; Ayala, V.; Ferrer, I.
Glial fibrillary acidic protein is a major target of glycoxidative and lipoxidative damage in Pick's disease.
JOURNAL OF NEUROCHEMISTRY 99 177-185. .
Podlesniy, P; Kichev, A; Pedraza, C; Saurat, J; Encinas, M; Perez, B; Ferrer, I; Espinet, C
Pro-NGF from Alzheimer's disease and normal human brain displays distinctive abilities to induce processing and nuclear translocation of intracellular domain of p75NTR and apoptosis.
AMERICAN JOURNAL OF PATHOLOGY 169 119-131. .
Sanz, Alberto; Caro, Pilar; Ayala, Victoria; Portero-Otin, Manuel; Pamplona, Reinald; Barja, Gustavo
Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins.
FASEB JOURNAL 20 1064-1073. .
Pamplona, R.; Barja, G.
Mitochondrial oxidative stress, aging and caloric restriction: the protein and methionine connection.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1757 496-508. .