Fisiopatologia metabòlica
Responsable de grup
Publicacions (413)
Martinez, Anna; Portero-Otin, Manuel; Pamplona, Reinald; Ferrer, Isidre
Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates.
BRAIN PATHOLOGY 20 281-297. .
Caldero, J.; Brunet, N.; Tarabal, O.; Piedrafita, L.; Hereu, M.; Ayala, V.; Esquerda, J. E.
Lithium prevents excitotoxic cell death of motoneurons in organotypic slice cultures of spinal cord.
NEUROSCIENCE 165 1353-1369. .
Belen Granado-Serrano, Ana; Angeles Martin, Maria; Haegeman, Guy; Goya, Luis; Bravo, Laura; Ramos, Sonia
Epicatechin induces NF-kappa B, activator rotein-1 (aP-1) and nuclear transcription factor erythroid 2p45-related factor-2 (Nrf2) via phosphatidylinositol-3-kinase/protein kinase B (PI3K/aKT) and extracellular regulated kinase (ERK) signalling in HepG2 cells
BRITISH JOURNAL OF NUTRITION 103 168-179. .
Muntane, Gerard; Janue, Anna; Fernandez, Nuria; Odena, Maria Antonia; Oliveira, Eliandre; Boluda, Susana; Portero-Otin, Manuel; Naudi, Alba; Boada, Jordi; Pamplona, Reinald; Ferrer, Isidre
Modification of brain lipids but not phenotype in alpha-synucleinopathy transgenic mice by long-term dietary n-3 fatty acids.
NEUROCHEMISTRY INTERNATIONAL 56 318-328. .
Terni, Beatrice; Boada, Jordi; Portero-Otin, Manuel; Pamplona, Reinald; Ferrer, Isidro
Mitochondrial ATP-synthase in the entorhinal cortex is a target of oxidative stress at stages I/II of Alzheimer's disease pathology.
BRAIN PATHOLOGY 20 222-233. .
Fernandez, Liana Lisboa; Carmona, Marga; Portero-Otin, Manuel; Naudi, Alba; Pamplona, Reinald; Schroeder, Nadja; Ferrer, Isidro
Effects of increased iron intake during the neonatal period on the brain of adult AbetaPP/PS1 transgenic mice.
JOURNAL OF ALZHEIMERS DISEASE 19 1069-1080. .
Quiles, Jose L.; Pamplona, Reinald; Carmen Ramirez-Tortosa, M.; Naudi, Alba; Portero-Otin, Manuel; Araujo-Nepomuceno, Eduardo; Lopez-Frias, Magdalena; Battino, Maurizio; Ochoa, Julio J.
Coenzyme Q addition to an n-6 PUFA-rich diet resembles benefits on age-related mitochondrial DNA deletion and oxidative stress of a MUFA-rich diet in rat heart.
MECHANISMS OF AGEING AND DEVELOPMENT 131 38-47. .
Barrantes, Francisco J.; Bermudez, V.; Borroni, M. V.; Antollini, S. S.; Pediconi, M. F.; Baier, J. C.; Bonini, I.; Gallegos, C.; Roccamo, A. M.; Valles, A. S.; Ayala, V.; Kamerbeek, C.
Boundary Lipids In The Nicotinic acetylcholine Receptor Microenvironment
JOURNAL OF MOLECULAR NEUROSCIENCE 40 87-90. .
Belen Granado-Serrano, Ana; Angeles Martin, Maria; Bravo, Laura; Goya, Luis; Ramos, Sonia
Quercetin Modulates NF-kappa B and aP-1/JNK Pathways to Induce Cell Death in Human Hepatoma Cells
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL 62 390-401. .
Kichev, Anton; Ilieva, Ekaterina V.; Pinol-Ripoll, Gerard; Podlesniy, Petar; Ferrer, Isidro; Portero-Otin, Manuel; Pamplona, Reinald; Espinet, Carme
Cell death and learning impairment in mice caused by in vitro modified pro-NGF can be related to its increased oxidative modifications in Alzheimer disease.
AMERICAN JOURNAL OF PATHOLOGY 175 2574-2585. .
Caro, Pilar; Gomez, Jose; Sanchez, Ines; Naudi, Alba; Ayala, Victoria; Lopez-Torres, Monica; Pamplona, Reinald; Barja, Gustavo
Forty percent methionine restriction decreases mitochondrial oxygen radical production and leak at complex I during forward electron flow and lowers oxidative damage to proteins and mitochondrial DNA in rat kidney and brain mitochondria.
REJUVENATION RESEARCH 12 421-434. .
Negre-Salvayre, Anne; Salvayre, Robert; Auge, Nathalie; Pamplona, Reinald; Portero-Otin, Manuel
Hyperglycemia and glycation in diabetic complications.
ANTIOXIDANTS & REDOX SIGNALING 11 3071-3109. .