Bioinformatics and Computational Biology (BIO2COMP)

Training and consultancy

• Consultancy services to researchers for the approach of bioinformatics activities in the application for project funding and in the planning of their experiments with a view to an adequate subsequent bioinformatics treatment.
• Personalised and group training in bioinformatics and mathematical modelling.
• Advice and support to users of bioinformatics tools and methods.

Standard analysis

• De novo assembly and annotation of prokaryotic genomes.
• Reference genome variant analysis in prokaryotes and eukaryotes.
• Gene expression analysis (MicroArray & RNAseq) for identification of differentially expressed genes.
• Analysis and optimisation of expression of biological sequences (use of most frequent codons).
• Modelling and prediction of protein structures.
• Data visualisation in maps of biological networks.

Specialised analysis

• Qualitative and quantitative analysis of results of omics experiments.
• Data analysis.
• Other non-standard projects.

Training and consultancy

• Consultancy services to researchers for the approach of computational biology activities in the application for project funding and in the planning of their experiments with a view to an adequate subsequent bioinformatics treatment.
• Personalised and group training in computational biology methods.
• Advice and support to users in the use of mathematical modelling software in biology, biomedicine and biotechnology.

Specialised analyses

• Creation of "digital twins" of biological processes for analysis and optimisation.
• Compartmental modelling.
• Sensitivity analysis and evaluation of 'what if...' scenarios. (in silico experiments).

Equipment

• 2 Servers, each with 2 Intel Xeon processors (24 compute nodes) at 2.0 GHz, 124 GB RAM, for intensive calculations.
• 4 HP Z series workstations, with Intel Xeon processors and 8 computation nodes.
• 3 HP high-performance PCs.